Mco Hospital Aids Private Limited

Polyglactin 910 is a synthetic, absorbable, sterile surgical suture composed of a copolymer made from 90% glycolide and 10% L-lactide. It is commonly known by the brand name VICRYL™, manufactured by Relyon, a subsidiary of MCo Hospital Aids Pvt Ltd.

This suture is typically braided and coated to enhance its handling properties and reduce tissue drag during passage. The coating often consists of a copolymer of poly (glycolide-co-L-lactide) and calcium stearate, which facilitates smooth passage through tissues and reliable knot security.

Polyglactin 910 sutures are available in both dyed (violet) and undyed forms. The violet dye, approved by the FDA, aids in visibility during surgical procedures.

In terms of tensile strength, Polyglactin 910 retains approximately 75% of its strength at 14 days post-implantation. Absorption occurs through hydrolysis, with complete absorption typically between 56 and 70 days.

This suture is indicated for use in general soft tissue approximation and/or ligation, including in ophthalmic procedures. However, it is not recommended for use in cardiovascular or neurological tissues.

Polyglactin 910 sutures are available in various sizes, ranging from USP 3-0 to 1, and can be equipped with different needle types, including taper point, cutting edge, and reverse cutting needles, to suit diverse surgical requirements.

Overall, Polyglactin 910 sutures are valued for their predictable absorption profile, excellent handling characteristics, and minimal tissue reaction, making them a preferred choice in various surgical procedures.

Polydioxanone sutures are synthetic, absorbable monofilament sutures made from the polyester poly(p-dioxanone). They are designed to provide extended wound support, making them suitable for soft tissue approximation in various surgical procedures, including pediatric cardiovascular surgery and ophthalmic surgery.

Key Characteristics:

• Tensile Strength: Polydioxanone sutures retain approximately 70% of their initial tensile strength at two weeks post-implantation, about 50% at four weeks, and around 25% at six weeks. This gradual loss of strength supports healing tissues over an extended period.
• Absorption Profile: These sutures are absorbed through hydrolysis, with complete absorption occurring between 180 to 210 days post-implantation. The predictable absorption rate ensures prolonged wound support during the critical healing phase.
• Handling and Knot Security: Polydioxanone sutures are known for their excellent pliability and handling characteristics, facilitating smooth passage through tissues and reliable knot security.
• Tissue Reaction: They elicit minimal tissue reaction, reducing the risk of inflammation and promoting favorable healing conditions.
• Color and Sizes: Typically available in violet for enhanced visibility during surgery, these sutures come in various sizes, ranging from USP 6/0 to USP 2, to accommodate different surgical needs.

Applications:

Polydioxanone sutures are particularly useful in situations where extended wound support is desirable. They are indicated for use in soft tissue approximation, including pediatric cardiovascular tissue where growth is expected, and ophthalmic surgery. However, they are not recommended for adult cardiovascular tissue and neurological tissue.

Overall, polydioxanone sutures offer a combination of prolonged tensile strength retention and predictable absorption, making them a preferred choice for procedures requiring extended wound support.

Catgut chromic suture is a type of absorbable surgical suture made from the natural fiber of sheep or goat intestines. The term "catgut" is a historical misnomer, as the material comes from animals like goats and sheep, not cats.

Chromic catgut is treated with chromium salts to slow down the absorption process, making it last longer in the body than plain catgut. It is commonly used in various medical and surgical procedures, especially in internal organs, gastrointestinal surgery, and ophthalmic surgery. Over time, the body absorbs the suture, so it doesn't require removal. It is known for its flexibility, ease of handling, and relatively low tissue reactivity.

Some characteristics of chromic catgut sutures include:

1. Absorbable: It is absorbed by the body through enzymatic breakdown, typically within 70-90 days.
2. Tensile strength: The suture maintains a good level of tensile strength initially, but it gradually weakens as the absorption process takes place.
3. Biocompatibility: While it is generally well-tolerated, it can cause some tissue inflammation in certain cases, especially in comparison to synthetic absorbable sutures.

It is often chosen for surgeries where long-term support is not necessary, and its natural fiber composition can offer advantages in specific contexts. However, due to the potential for tissue reactions and the advent of more advanced synthetic sutures, chromic catgut is used less frequently than in the past.

Natural Absorbable Sutures

(Catgut Chromatic/Plain) Natural Absorbable Suture

Product Benefits

• Predictable absorption guarenteed by higher collagen levels
• Monofilament finish due to precise polishing
• Smooth tissue passage due to uniform diameter
• Extended wound support ensured by uniform chromatization
• Maximum tensile strength achieved by rigorously controlled

Product Application

• This product is ideal for usage in gastroenterological, general
  and ob-gyn surgical procedures

Product Specifications

• This range is available in sizes 2 to 3-0, with and without the needle

   

Polyglactin 910 Rapid is a synthetic, absorbable, braided suture designed for situations requiring short-term wound support. Composed of a copolymer made from 90% glycolide and 10% L-lactide, it undergoes a unique irradiation process that accelerates its absorption rate compared to standard Polyglactin 910 sutures.

Key Characteristics:

• Rapid Absorption: Designed for quick absorption, providing wound support for approximately 7 to 10 days, with complete absorption typically occurring within 42 days.
• Tensile Strength: Retains about 50% of its initial tensile strength at 5 days post-implantation and loses all tensile strength by 10 to 14 days.
• Composition: Made from a copolymer of 90% glycolide and 10% L-lactide, coated with a copolymer of glycolide and lactide (Polyglactin 370) and calcium stearate, enhancing its handling properties and knot security.
• Minimal Tissue Reaction: Elicits only a mild tissue response during absorption, reducing the risk of inflammation and promoting smoother healing.
• Availability: Offered in both dyed (violet) and undyed forms, and in various sizes to accommodate different surgical needs.

Common Applications:

Polyglactin 910 Rapid sutures are particularly suited for procedures where short-term wound support is sufficient, such as:

• Superficial Soft Tissue Approximation: Ideal for skin closures, including episiotomies, circumcisions, and closure of oral mucosa.
• Pediatric Surgery: Beneficial in procedures involving children, where rapid healing is anticipated.
• Ophthalmic Procedures: Suitable for conjunctival suturing and other eye-related surgeries.

Advantages:

• Excellent Handling and Knotting Characteristics: The braided and coated structure ensures smooth tissue passage, easy knotting, and reliable knot security.
• Predictable Absorption: Absorbed through hydrolysis, providing a reliable and consistent absorption profile.
• Reduced Need for Suture Removal: As an absorbable suture, it eliminates the necessity for suture removal, enhancing patient comfort and compliance.

Considerations:

• Limited Duration of Wound Support: Not suitable for tissues requiring extended support beyond 10 days.
• Avoid in High-Tension Areas: Not recommended for use in cardiovascular or neurological tissues, or in areas subjected to significant mechanical stress.

In summary, Polyglactin 910 Rapid sutures offer a reliable solution for surgical scenarios necessitating short-term wound support, combining rapid absorption with favorable handling properties to facilitate efficient and effective wound closure.

Polyglycolic acid (PGA) sutures offer several advantages that make them a preferred choice in various surgical procedures:

• Absorbability: PGA sutures are absorbable, eliminating the need for suture removal. They degrade through hydrolysis, with absorption typically complete between 50 and 70 days.
• High Initial Tensile Strength: These sutures provide robust support during the critical wound healing period, maintaining approximately 75% of their tensile strength at two weeks and 25% at four weeks post-implantation.
• Minimal Tissue Reaction: PGA sutures elicit a minimal acute inflammatory reaction in tissues, followed by gradual encapsulation by fibrous connective tissue, which is beneficial for patient recovery.
• Excellent Handling and Knot Security: The braided and coated structure of PGA sutures ensures smooth passage through tissues, easy handling, and secure knot tying, enhancing surgical efficiency.
• Predictable Absorption: The consistent absorption profile of PGA sutures allows surgeons to anticipate the duration of wound support, facilitating appropriate suture selection based on tissue healing times.

These characteristics make PGA sutures suitable for a wide range of applications, including subcutaneous closures, abdominal surgeries, and thoracic surgeries. However, they may not be ideal for situations requiring extended tissue approximation beyond their absorption period. Therefore, the choice of suture material should be tailored to the specific needs of the surgical procedure and patient condition.

 

Poliglecaprone 25 is a synthetic, absorbable monofilament suture composed of a copolymer of glycolide and ε-caprolactone. It is commonly used for soft tissue approximation and ligation, particularly in subcuticular closures, due to its smooth passage through tissue and minimal tissue reaction.This suture maintains approximately 50–60% of its tensile strength at one week post-implantation and loses all tensile strength by the second week. Complete absorption occurs within 60 to 90 days through hydrolysis.Poliglecaprone 25 is available in both dyed (violet) and undyed (clear) forms and is sterilized using ethylene oxide. It is supplied for single-use only and meets the performance requirements defined in the United States Pharmacopeia for diameter, tensile strength, and sterility.While it offers excellent handling and knot security, its rapid loss of tensile strength makes it unsuitable for applications requiring long-term support, such as cardiovascular or neurological procedures. It is ideal for rapidly healing tissues and is often used in subcutaneous closures, skin repairs, and bowel or peritoneal procedures.Overall, poliglecaprone 25 sutures are valued for their pliability, predictable absorption, and minimal tissue reactivity, making them a preferred choice for many soft tissue approximation procedures.